LFM-A13
Code | Size | Price |
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TAR-T6217-2mg | 2mg | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6217-1mL | 1 mL * 10 mM (in DMSO) | £108.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6217-5mg | 5mg | £108.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6217-10mg | 10mg | £130.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6217-25mg | 25mg | £205.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6217-50mg | 50mg | £298.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6217-100mg | 100mg | £455.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
LFM-A13?IC50=2.5 μM?, a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.
CAS:
244240-24-2
Formula:
C11H8Br2N2O2
Molecular Weight:
360.005
Pathway:
Cell Cycle/Checkpoint; JAK/STAT signaling; Angiogenesis; Stem Cells; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
Purity:
0.999
SMILES:
CC(O)=C(/C#N)C(=O)Nc1cc(Br)ccc1Br
Target:
PLK; JAK; BTK
References
Uckun FM, et al. Clin Cancer Res. 2002, 8(5), 1224-1233.
Mahajan S, et al. J Biol Chem. 1999, 274(14), 9587-9599.
Wan J, Yu X, Niu J Q, et al. Inhibition of Bruton's Tyrosine Kinase Protects Against Burn Sepsis-Induced Intestinal Injury. Frontiers in Medicine. 2022, 9.
Bam R, et al. Am J Hematol. 2013, 88(6), 463-471.
Gilbert C, et al. J Immunol. 2003, 170(10), 5235-5243.