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TargetMol
Product Code: TAR-T6247
Supplier: TargetMol
CodeSizePrice
TAR-T6247-2mg2mg£103.00
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TAR-T6247-5mg5mg£124.00
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TAR-T6247-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T6247-10mg10mg£144.00
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TAR-T6247-25mg25mg£197.00
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TAR-T6247-50mg50mg£264.00
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TAR-T6247-100mg100mg£389.00
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TAR-T6247-200mg200mg£481.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NMS-P937 (NMS1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.
CAS:
1034616-18-6
Formula:
C24H27F3N8O3
Molecular Weight:
532.528
Pathway:
Cell Cycle/Checkpoint; Apoptosis
Purity:
0.9976
SMILES:
CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2ncc3CCc4c(nn(CCO)c4-c3n2)C(N)=O)c1
Target:
Apoptosis; PLK

References

Valsasina B, et al. Mol Cancer Ther. 2012, 11(4), 12006-12016. Beria I, et al. Bioorg Med Chem Lett. 2011, 21(10), 2969-2974.