Tie2 kinase inhibitor 1

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TargetMol
Product Code: TAR-T6335
Supplier: TargetMol
CodeSizePrice
TAR-T6335-1mg1mg£120.00
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TAR-T6335-2mg2mg£141.00
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TAR-T6335-1mL1 mL * 10 mM (in DMSO)£222.00
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TAR-T6335-5mg5mg£222.00
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TAR-T6335-10mg10mg£322.00
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TAR-T6335-25mg25mg£502.00
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TAR-T6335-50mg50mg£693.00
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TAR-T6335-100mg100mg£938.00
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TAR-T6335-500mg500mg£1,813.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Tie2 kinase inhibitor, an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38.
CAS:
948557-43-5
Formula:
C26H21N3O2S
Molecular Weight:
439.53
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9982
SMILES:
COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1ccc(cc1)S(C)=O
Target:
Tie-2

References

Semones M, et al. Bioorg Med Chem Lett, 2007, 17(17), 4756-4760.