AG14361

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TargetMol
Product Code: TAR-T6339
Supplier: TargetMol
CodeSizePrice
TAR-T6339-1mg1mg£108.00
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TAR-T6339-2mg2mg£123.00
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TAR-T6339-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T6339-5mg5mg£185.00
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TAR-T6339-10mg10mg£279.00
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TAR-T6339-25mg25mg£475.00
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TAR-T6339-50mg50mg£659.00
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TAR-T6339-100mg100mg£863.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).
CAS:
328543-09-5
Formula:
C19H20N4O
Molecular Weight:
320.396
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9877
SMILES:
CN(C)Cc1ccc(cc1)-c1nc2cccc3C(=O)NCCn1c23
Target:
PARP

References

Shi F, Wu L, Cui D, et al.LncFALEC recruits ART5/PARP1 and promotes castration-resistant prostate cancer through enhancing PARP1-meditated self PARylation.Cellular Oncology.2023: 1-16. Curtin NJ, et al. Clin Cancer Res, 2004, 10(3), 881-9. Calabrese CR, et al. J Natl Cancer Inst, 2004, 96(1), 56-67. Smith LM, et al. Clin Cancer Res, 2005, 11(23), 8449-57.