AZD3514
Code | Size | Price |
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TAR-T6400-5mg | 5mg | £123.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6400-1mL | 1 mL * 10 mM (in DMSO) | £131.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
CAS:
1240299-33-5
Formula:
C25H32F3N7O2
Molecular Weight:
519.573
Pathway:
Endocrinology/Hormones
Purity:
0.966
SMILES:
CC(=O)N1CCN(CCOc2ccc(cc2)C2CCN(CC2)C2=Nn3c(CC2)nnc3C(F)(F)F)CC1
Target:
Androgen Receptor
References
Bradbury RH, et al. Bioorg Med Chem Lett, 2013, 23(7), 1945-1948.
Sarah A. Loddick, et al. Cancer Res, 2012, 72(8 Suppl), Abstract nr 3848.