Bindarit

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TargetMol
Product Code: TAR-T6413
Supplier: TargetMol
CodeSizePrice
TAR-T6413-1mg1mg£112.00
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TAR-T6413-2mg2mg£131.00
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TAR-T6413-5mg5mg£171.00
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TAR-T6413-10mg10mg£229.00
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Quantity:
TAR-T6413-1mL1 mL * 10 mM (in DMSO)£245.00
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TAR-T6413-25mg25mg£338.00
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Quantity:
TAR-T6413-50mg50mg£470.00
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TAR-T6413-100mg100mg£643.00
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Quantity:
TAR-T6413-500mg500mg£1,243.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Bindarit displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.
CAS:
130641-38-2
Formula:
C19H20N2O3
Molecular Weight:
324.38
Pathway:
Immunology/Inflammation; Microbiology/Virology
Purity:
0.9871
SMILES:
CC(C)(OCc1nn(Cc2ccccc2)c2ccccc12)C(O)=O
Target:
CCR

References

Shi Z, Yu P, Lin W J, et al.Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes.Neuron.2023 Wu R, Zhang P A, Liu X, et al. Decreased miR-325-5p Contributes to Visceral Hypersensitivity Through Post-transcriptional Upregulation of CCL2 in Rat Dorsal Root Ganglia[J]. Neuroscience bulletin. 2019 Apr 12: 1-11. Sironi M, et al. Eur Cytokine Netw, 1999, 10(3), 437-442. Guglielmotti A, et al. Inflamm Res, 2002, 51(5), 252-258. Grassia G, et al. Cardiovasc Res, 2009, 84(3), 485-493. Wu R, Zhang P A, Liu X, et al. Decreased miR-325-5p Contributes to Visceral Hypersensitivity Through Post-transcriptional Upregulation of CCL2 in Rat Dorsal Root Ganglia. Neuroscience Bulletin. 2019 Apr 12: 1-11 Zoja C, et al. Kidney Int, 1998, 53(3), 726-734. Gazzaniga S, et al. J Invest Dermatol, 2007, 127(8), 2031-2041.