MG 149

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TargetMol
Product Code: TAR-T6584
Supplier: TargetMol
CodeSizePrice
TAR-T6584-1mg1mg£109.00
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TAR-T6584-2mg2mg£125.00
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TAR-T6584-5mg5mg£148.00
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TAR-T6584-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T6584-10mg10mg£214.00
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TAR-T6584-25mg25mg£345.00
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TAR-T6584-50mg50mg£509.00
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TAR-T6584-100mg100mg£703.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
CAS:
1243583-85-8
Formula:
C22H28O3
Molecular Weight:
340.463
Pathway:
Chromatin/Epigenetic; ; Apoptosis
Purity:
0.991
SMILES:
CCCCCCCc1ccc(CCc2cccc(O)c2C(O)=O)cc1
Target:
Apoptosis; Epigenetic Reader Domain; Histone Acetyltransferase

References

Ghizzoni M, et al. 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. Eur J Med Chem. 2012 Jan;47(1):337-44.