NH125

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TargetMol
Product Code: TAR-T6605
Supplier: TargetMol
CodeSizePrice
TAR-T6605-1mg1mg£98.00
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TAR-T6605-2mg2mg£109.00
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TAR-T6605-5mg5mg£135.00
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TAR-T6605-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T6605-10mg10mg£168.00
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TAR-T6605-25mg25mg£294.00
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TAR-T6605-50mg50mg£454.00
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TAR-T6605-100mg100mg£624.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
CAS:
278603-08-0
Formula:
C27H45IN2
Molecular Weight:
524.575
Pathway:
Tyrosine Kinase/Adaptors; Neuroscience; Chromatin/Epigenetic; Autophagy; Cytoskeletal Signaling; Microbiology/Virology
Purity:
0.9804
SMILES:
[I-].CCCCCCCCCCCCCCCCn1cc[n+](Cc2ccccc2)c1C
Target:
CaMK; Virus Protease; PKA; Antibacterial; PKC; Autophagy; Antifungal

References

Usui T, et al. Am J Physiol Heart Circ Physiol. 2013, 305(5), H756-768 Arora S, et al. Cancer Res. 2003, 63(20), 6894-6899. Yamamoto K, et al. Biosci Biotechnol Biochem. 2000, 64(4), 919-923. Cheng Y, et al. Autophagy. 2013, 9(2), 208-219.