PYR-41

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TargetMol
Product Code: TAR-T6629
Supplier: TargetMol
CodeSizePrice
TAR-T6629-2mg2mg£97.00
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TAR-T6629-5mg5mg£112.00
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TAR-T6629-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T6629-10mg10mg£134.00
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TAR-T6629-25mg25mg£203.00
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TAR-T6629-50mg50mg£333.00
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Quantity:
TAR-T6629-100mg100mg£470.00
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TAR-T6629-200mg200mg£622.00
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TAR-T6629-500mg500mg£938.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
CAS:
418805-02-4
Formula:
C17H13N3O7
Molecular Weight:
371.305
Pathway:
Ubiquitination; Apoptosis
Purity:
0.9924
SMILES:
CCOC(=O)c1ccc(cc1)N1NC(=O)C(=Cc2ccc(o2)[N+]([O-])=O)C1=O
Target:
Apoptosis; E1/E2/E3 Enzyme

References

Kapuria V, et al. Biochem Pharmacol, 2011, 82(4), 341-349. Yang Y, et al. Cancer Res, 2007, 67(19), 9472-9481.