Ro 31-8220 Mesylate
Code | Size | Price |
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TAR-T6643-1mg | 1mg | £106.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T6643-2mg | 2mg | £120.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6643-5mg | 5mg | £149.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T6643-1mL | 1 mL * 10 mM (in DMSO) | £185.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6643-10mg | 10mg | £201.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6643-25mg | 25mg | £276.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6643-50mg | 50mg | £356.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6643-100mg | 100mg | £494.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Ro 31-8220 is a pan-PKC inhibitor for PKC-α/βI/βII/γ/ε (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.
CAS:
138489-18-6
Formula:
C26H27N5O5S2
Molecular Weight:
553.65
Pathway:
Cytoskeletal Signaling; Chromatin/Epigenetic
Purity:
0.9918
SMILES:
CS(O)(=O)=O.Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12
Target:
PKC
References
Chen X, Xi Z, Liang H, et al. Melatonin prevents mice cortical astrocytes from hemin-induced toxicity through activating Nrf2/HO-1 signaling in vitro. Frontiers in Neuroscience. 2019, 13: 760
Kim SY, et al. BMB Rep. 2011, 44(2), 140-145.
Karunakaran D, et al. J Biol Chem. 2013, 288(7), 5186-5197.
Davies SP, et al. Biochem J. 2000, 351(Pt 1), 95-105.
Courage C, et al. Br J Cancer. 1995, 71(4), 697-704.
Chen X, Xi Z, Liang H, et al. Melatonin prevents mice cortical astrocytes from hemin-induced toxicity through activating Nrf2/HO-1 signaling in vitro[J]. Frontiers in Neuroscience. 2019, 13: 760.
Wilkinson SE, et al. Biochem J. 1993, 294 ( Pt 2), 335-337.