SB273005
Code | Size | Price |
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TAR-T6657-2mg | 2mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6657-5mg | 5mg | £571.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6657-1mL | 1 mL * 10 mM (in DMSO) | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6657-25mg | 25mg | £1,371.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6657-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
CAS:
205678-31-5
Formula:
C22H24F3N3O4
Molecular Weight:
451.446
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
CNc1cccc(CCOc2ccc3C[C@@H](CC(O)=O)C(=O)N(CC(F)(F)F)Cc3c2)n1
Target:
Integrin
References
Miller WH, et al. J Med Chem. 2000, 43(1), 22-26.
Gomes N, et al. Clin Exp Metastasis. 2004, 21(6), 553-561.
Badger AM, et al. Arthritis Rheum. 2001, 44(1), 128-137.
Rehm S, et al. Toxicol Pathol. 2007, 35(7), 958-971.
Wang S, et al. Exp Ther Med. 2014, 7(6), 1677-1682.