AMG 925

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TargetMol
Product Code: TAR-T6756
Supplier: TargetMol
CodeSizePrice
TAR-T6756-1mg1mg£95.00
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Quantity:
TAR-T6756-2mg2mg£105.00
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Quantity:
TAR-T6756-5mg5mg£125.00
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Quantity:
TAR-T6756-10mg10mg£148.00
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Quantity:
TAR-T6756-25mg25mg£209.00
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Quantity:
TAR-T6756-50mg50mg£302.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.
CAS:
1401033-86-0
Formula:
C26H29N7O2
Molecular Weight:
471.565
Pathway:
Angiogenesis; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
Purity:
0.9942
SMILES:
C[C@H]1CC[C@@H](CC1)n1c2cnccc2c2cnc(Nc3ccc4CN(CCc4n3)C(=O)CO)nc12
Target:
FLT; CDK

References

Xiaoqi Chen, et al. Fused tricyclic dual inhibitors of cdk 4/6 and flt3. WO 2012129344 A1