TCS7010

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TargetMol
Product Code: TAR-T6767
Supplier: TargetMol
CodeSizePrice
TAR-T6767-1mg1mg£96.00
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TAR-T6767-2mg2mg£107.00
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TAR-T6767-5mg5mg£128.00
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TAR-T6767-1mL1 mL * 10 mM (in DMSO)£146.00
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TAR-T6767-10mg10mg£173.00
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TAR-T6767-25mg25mg£255.00
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TAR-T6767-50mg50mg£390.00
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TAR-T6767-100mg100mg£546.00
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TAR-T6767-500mg500mg£1,099.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
CAS:
1158838-45-9
Formula:
C31H31ClFN7O2
Molecular Weight:
588.08
Pathway:
Cell Cycle/Checkpoint; Chromatin/Epigenetic; Apoptosis
Purity:
0.9969
SMILES:
CCN1CCN(CC1)C(=O)Cc1ccc(Nc2ncc(F)c(Nc3ccc(cc3)C(=O)Nc3ccccc3Cl)n2)cc1
Target:
Apoptosis; Aurora Kinase

References

Rawson TE, et al. J Med Chem, 2008, 51(15), 4465-4475. Yuan H, et al. Carcinogenesis, 2012, 33(2), 285-293. Kwiatkowski N, et al. ACS Chem Biol, 2012, 7(1), 185-196. Aliagas-Martin I, et al. J Med Chem, 2009, 52(10), 3300-3307.