AZD3839 free base

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TargetMol

Product Code: TAR-T6772

Product Group: Inhibitors and Activators

Supplier: TargetMol

Code	Size	Price

TAR-T6772-50mg

50mg

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Quantity:

TAR-T6772-1mg

1mg

£109.00

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Quantity:

TAR-T6772-2mg

2mg

£125.00

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Quantity:

TAR-T6772-5mg

5mg

£164.00

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Quantity:

TAR-T6772-1mL

1 mL * 10 mM (in DMSO)

£169.00

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Quantity:

TAR-T6772-10mg

10mg

£213.00

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Quantity:

TAR-T6772-25mg

25mg

£362.00

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Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Shipping:

cool pack

Storage:

-20℃

Images

1 / 1

Documents

Further Information

Bioactivity:

AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.

CAS:

1227163-84-9

Formula:

C24H16F3N5

Molecular Weight:

431.422

Pathway:

Neuroscience

Purity:

0.9996

SMILES:

NC1=N[C@@](c2cccc(F)c12)(c1cccc(c1)-c1cncnc1)c1ccnc(c1)C(F)F

Target:

Beta-Secretase; BACE

References

Swahn BM, et al. J Med Chem. 2012, 55(21), 9346-9361. Jeppsson F, et al. J Biol Chem. 2012, 287(49), 41245-41257.