AZD-8835

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TargetMol
Product Code: TAR-T6774
Supplier: TargetMol
CodeSizePrice
TAR-T6774-1mg1mg£95.00
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TAR-T6774-2mg2mg£106.00
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TAR-T6774-5mg5mg£128.00
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TAR-T6774-1mL1 mL * 10 mM (in DMSO)£140.00
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TAR-T6774-10mg10mg£155.00
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TAR-T6774-25mg25mg£230.00
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TAR-T6774-50mg50mg£303.00
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TAR-T6774-100mg100mg£470.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AZD8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).
CAS:
1620576-64-8
Formula:
C22H31N9O3
Molecular Weight:
469.55
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9849
SMILES:
CCn1nc(nc1-c1cnc(N)c(n1)-c1nnc(o1)C(C)(C)C)C1CCN(CC1)C(=O)CCO
Target:
PI3K

References

Bernard Barlaam, et al. Bioorganic & Medicinal Chemistry Letters. 2015, 25(22):5155-5162. Hudson K, et al. Mol Cancer Ther. 2016, 15(5):877-89.