BAY 41-2272

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TargetMol
Product Code: TAR-T6775
Supplier: TargetMol
CodeSizePrice
TAR-T6775-1mg1mg£98.00
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TAR-T6775-2mg2mg£108.00
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TAR-T6775-1mL1 mL * 10 mM (in DMSO)£131.00
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Quantity:
TAR-T6775-5mg5mg£131.00
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Quantity:
TAR-T6775-10mg10mg£179.00
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Quantity:
TAR-T6775-25mg25mg£301.00
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TAR-T6775-50mg50mg£438.00
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TAR-T6775-100mg100mg£611.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.
CAS:
256376-24-6
Formula:
C20H17FN6
Molecular Weight:
360.396
Pathway:
GPCR/G Protein
Purity:
0.9986
SMILES:
Nc1nc(ncc1C1CC1)-c1nn(Cc2ccccc2F)c2ncccc12
Target:
Guanylate cyclase

References

Tuttle TR, et al. The cyclic GMP/protein kinase G pathway as a therapeutic target in head and neck squamous cell carcinoma. Cancer Lett. 2016 Jan 28;370(2):279-85. Nunes KP, et al. J Pharmacol Exp Ther. 2015, 353(2), 330-339. Soeiro-Pereira PV, et al. Mem Inst Oswaldo Cruz. 2015, 110(1), 75-85. Stasch JP, et al. Nature. 2001, 410(6825), 212-215. Kalsi JS, et al. J Urol. 2003, 169(2), 761-766. Becker EM, et al. BMC Pharmacol. 2001, 1, 13.