G007-LK

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TargetMol
Product Code: TAR-T6842
Supplier: TargetMol
CodeSizePrice
TAR-T6842-1mg1mg£107.00
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TAR-T6842-2mg2mg£122.00
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TAR-T6842-5mg5mg£151.00
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TAR-T6842-1mL1 mL * 10 mM (in DMSO)£171.00
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TAR-T6842-10mg10mg£206.00
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TAR-T6842-25mg25mg£352.00
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TAR-T6842-50mg50mg£519.00
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TAR-T6842-100mg100mg£701.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.
CAS:
1380672-07-0
Formula:
C25H16ClN7O3S
Molecular Weight:
529.96
Pathway:
DNA Damage/DNA Repair; Cytoskeletal Signaling; Chromatin/Epigenetic; Stem Cells
Purity:
0.9862
SMILES:
CS(=O)(=O)c1ccc(nc1)-c1nnc(C=Cc2nnc(o2)-c2ccc(cc2)C#N)n1-c1ccccc1Cl
Target:
PARP; Wnt/beta-catenin

References

Voronkov A, et al. J Med Chem, 2013, 56(7), 32012-3023. Lau T, et al. Cancer Res, 2013, 73(10), 3132-3144.