GDC-0623

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TargetMol
Product Code: TAR-T6843
Supplier: TargetMol
CodeSizePrice
TAR-T6843-1mg1mg£109.00
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TAR-T6843-2mg2mg£124.00
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TAR-T6843-1mL1 mL * 10 mM (in DMSO)£168.00
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Quantity:
TAR-T6843-5mg5mg£168.00
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TAR-T6843-10mg10mg£229.00
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TAR-T6843-25mg25mg£341.00
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TAR-T6843-50mg50mg£450.00
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TAR-T6843-100mg100mg£614.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
CAS:
1168091-68-6
Formula:
C16H14FIN4O3
Molecular Weight:
456.216
Pathway:
Apoptosis; MAPK
Purity:
0.9895
SMILES:
OCCONC(=O)c1ccc2cncn2c1Nc1ccc(I)cc1F
Target:
Apoptosis; MEK

References

Zaanan A, et al. J Biol Chem. 2015. doi/10.1074/jbc.M115.657833. Hatzivassiliou G, et al. Nature. 2013, 501(7466), 232-236.