GSK481

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TargetMol
Product Code: TAR-T6852
Supplier: TargetMol
CodeSizePrice
TAR-T6852-1mg1mg£102.00
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TAR-T6852-2mg2mg£114.00
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TAR-T6852-1mL1 mL * 10 mM (in DMSO)£135.00
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TAR-T6852-5mg5mg£148.00
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TAR-T6852-10mg10mg£193.00
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TAR-T6852-25mg25mg£309.00
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Quantity:
TAR-T6852-50mg50mg£475.00
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TAR-T6852-100mg100mg£659.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
GSK481 is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.
CAS:
1622849-58-4
Formula:
C21H19N3O4
Molecular Weight:
377.4
Pathway:
NF-κb; Apoptosis
Purity:
0.9971
SMILES:
CN1c2ccccc2OC[C@H](NC(=O)c2cc(Cc3ccccc3)on2)C1=O
Target:
RIP kinase

References

Harris PA, et al. J Med Chem. 2016, 59(5):2163-2178.