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TargetMol
Product Code: TAR-T6866
Supplier: TargetMol
CodeSizePrice
TAR-T6866-1mg1mg£95.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T6866-2mg2mg£105.00
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TAR-T6866-5mg5mg£128.00
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TAR-T6866-1mL1 mL * 10 mM (in DMSO)£149.00
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Quantity:
TAR-T6866-10mg10mg£164.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6866-25mg25mg£269.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6866-50mg50mg£369.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6866-100mg100mg£550.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.
CAS:
853299-07-7
Formula:
C24H26F3N7O2
Molecular Weight:
501.514
Pathway:
Cell Cycle/Checkpoint
Purity:
0.993
SMILES:
CN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc(N)n4)cc3)cc2C(F)(F)F)CC1
Target:
CDK

References

Meng T G, Lei W L, Li J, et al. Degradation of Ccnb3 is essential for maintenance of MII arrest in oocyte[J]. Biochemical and Biophysical Research Communications. 2020, 521(1): 265-269 Alexander LT, et al. ACS Chem Biol. 2015, 10(9), 2116-2125. Meng T G, Lei W L, Li J, et al. Degradation of Ccnb3 is essential for maintenance of MII arrest in oocyte. Biochemical and Biophysical Research Communications. 2020, 521(1): 265-269