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TargetMol
Product Code: TAR-T6867
Supplier: TargetMol
CodeSizePrice
TAR-T6867-2mg2mg£103.00
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TAR-T6867-5mg5mg£124.00
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TAR-T6867-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T6867-10mg10mg£144.00
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TAR-T6867-25mg25mg£206.00
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TAR-T6867-50mg50mg£282.00
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TAR-T6867-100mg100mg£389.00
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TAR-T6867-500mg500mg£828.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
KD025 is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).
CAS:
911417-87-3
Formula:
C26H24N6O2
Molecular Weight:
452.518
Pathway:
Cytoskeletal Signaling; Stem Cells; Cell Cycle/Checkpoint
Purity:
0.9859
SMILES:
CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1
Target:
ROCK

References

Zanin-Zhorov A, et al. Proc Natl Acad Sci U S A. 2014, 111(47), 16814-16819. Flynn R, et al. Blood. 2016. pii: blood-2015-10-678706. Lee JH, et al. Ann Clin Transl Neurol. 2014, 1(1), 2-14.