LJH685

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TargetMol
Product Code: TAR-T6877
Supplier: TargetMol
CodeSizePrice
TAR-T6877-1mg1mg£97.00
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TAR-T6877-2mg2mg£107.00
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TAR-T6877-5mg5mg£136.00
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TAR-T6877-1mL1 mL * 10 mM (in DMSO)£145.00
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TAR-T6877-10mg10mg£189.00
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TAR-T6877-25mg25mg£308.00
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TAR-T6877-50mg50mg£449.00
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TAR-T6877-100mg100mg£623.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM).
CAS:
1627710-50-2
Formula:
C22H21F2N3O
Molecular Weight:
381.427
Pathway:
PI3K/Akt/mTOR signaling; MAPK; Apoptosis
Purity:
0.98
SMILES:
CN1CCN(CC1)c1ccc(cc1)-c1ccncc1-c1cc(F)c(O)c(F)c1
Target:
Apoptosis; S6 Kinase

References

Aronchik I, et al. Mol Cancer Res. 2014, 12(5), 803-812.