N6022

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TargetMol
Product Code: TAR-T6901
Supplier: TargetMol
CodeSizePrice
TAR-T6901-1mg1mg£103.00
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TAR-T6901-2mg2mg£115.00
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TAR-T6901-5mg5mg£148.00
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TAR-T6901-1mL1 mL * 10 mM (in DMSO)£151.00
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TAR-T6901-10mg10mg£183.00
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TAR-T6901-25mg25mg£290.00
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TAR-T6901-50mg50mg£434.00
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TAR-T6901-100mg100mg£606.00
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TAR-T6901-500mg500mg£1,211.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
N6022(IC50 of 8 nM) is an effective, reversible, and selective S-Nitrosoglutathione reductase(GSNOR) inhibitor.
CAS:
1208315-24-5
Formula:
C24H22N4O3
Molecular Weight:
414.465
Pathway:
Metabolism
Purity:
0.9832
SMILES:
Cc1cc(ccc1-n1c(CCC(O)=O)ccc1-c1ccc(cc1)-n1ccnc1)C(N)=O
Target:
GSNOR

References

Liu Q, Gu T, Su L Y, et al. GSNOR facilitates antiviral innate immunity by restricting TBK1 cysteine S-nitrosation. Redox Biology. 2021: 102172. Green LS, et al. Biochemistry. 2012, 51(10), 2157-2168 Sun X, et al. ACS Med Chem Lett. 2011, 2(5), 402-406.