Olmutinib

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TargetMol
Product Code: TAR-T6918
Supplier: TargetMol
CodeSizePrice
TAR-T6918-2mg2mg£97.00
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TAR-T6918-5mg5mg£112.00
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TAR-T6918-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T6918-10mg10mg£136.00
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TAR-T6918-25mg25mg£182.00
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TAR-T6918-50mg50mg£222.00
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TAR-T6918-100mg100mg£309.00
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TAR-T6918-200mg200mg£461.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Olmutinib is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
CAS:
1353550-13-6
Formula:
C26H26N6O2S
Molecular Weight:
486.59
Pathway:
JAK/STAT signaling; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9927
SMILES:
CN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)c3sccc3n2)cc1
Target:
EGFR; BTK

References

Wang S, et al. J Hematol Oncol. 2016, 9: 34.