ONO-4059 analog

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TargetMol
Product Code: TAR-T6921
Supplier: TargetMol
CodeSizePrice
TAR-T6921-1mg1mg£101.00
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TAR-T6921-2mg2mg£114.00
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TAR-T6921-5mg5mg£142.00
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TAR-T6921-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T6921-10mg10mg£189.00
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TAR-T6921-25mg25mg£306.00
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TAR-T6921-50mg50mg£462.00
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TAR-T6921-100mg100mg£630.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
ONO-4059 analogue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.
CAS:
1351635-67-0
Formula:
C25H24N6O3
Molecular Weight:
456.506
Pathway:
Apoptosis; Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9925
SMILES:
Nc1ncnc2n([C@H]3CCCN(C3)C(=O)C=C)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12
Target:
Apoptosis; BTK

References

Yasuhiro T, et al. Blood, 2013, 122 (21), 5151- 5151.