PD0166285

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TargetMol
Product Code: TAR-T6931
Supplier: TargetMol
CodeSizePrice
TAR-T6931-1mg1mg£112.00
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TAR-T6931-2mg2mg£129.00
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TAR-T6931-5mg5mg£177.00
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TAR-T6931-1mL1 mL * 10 mM (in DMSO)£189.00
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TAR-T6931-10mg10mg£239.00
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TAR-T6931-25mg25mg£442.00
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TAR-T6931-50mg50mg£615.00
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TAR-T6931-100mg100mg£846.00
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TAR-T6931-500mg500mg£1,621.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.
CAS:
185039-89-8
Formula:
C26H27Cl2N5O2
Molecular Weight:
512.44
Pathway:
Cell Cycle/Checkpoint; Apoptosis
Purity:
0.9959
SMILES:
CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1
Target:
Apoptosis; Wee1; Chk

References

Wang Y, et al. Cancer Res. 2001, 61(22):8211-8217. Mir SE, et al. Cancer Cell. 2010, 18(3):244-257. Hashimoto O, et al. BMC Cancer. 2006, 6:292.