TargetMol

Corynoxeine

Product Code:
 
TAR-T6S0655
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S0655-5mg5mg£180.00
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TAR-T6S0655-10mg10mg£268.00
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TAR-T6S0655-25mg25mg£413.00
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TAR-T6S0655-50mg50mg£589.00
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TAR-T6S0655-100mg100mg£848.00
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This product comes from: United States.
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Further Information

Bioactivity:
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.
CAS:
630-94-4
Formula:
C22H26N2O4
Molecular Weight:
382.46
Pathway:
MAPK
Purity:
0.9868
SMILES:
COC=C(/[C@H]1C[C@@H]2N(CC[C@]22C(=O)Nc3ccccc23)C[C@@H]1C=C)C(=O)OC
Target:
ERK

References

Kim T J , Lee J H , Lee J J , et al. Corynoxeine Isolated from the Hook of Uncaria rhynchophylla Inhibits Rat Aortic Vascular Smooth Muscle Cell Proliferation through the Blocking of Extracellular Signal Regulated Kinase 1/2 Phosphorylation[J]. Biological & Pharmaceutical Bulletin, 2008, 31(11):2073-2078.