Selisistat S-enantiomer

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TargetMol
Product Code: TAR-T7058
Supplier: TargetMol
CodeSizePrice
TAR-T7058-1mg1mg£193.00
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TAR-T7058-2mg2mg£252.00
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TAR-T7058-5mg5mg£351.00
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TAR-T7058-1mL1 mL * 10 mM (in DMSO)£390.00
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TAR-T7058-10mg10mg£470.00
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TAR-T7058-25mg25mg£707.00
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TAR-T7058-50mg50mg£978.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Selisistat S-enantiomer is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.
CAS:
848193-68-0
Formula:
C13H13ClN2O
Molecular Weight:
248.71
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9969
SMILES:
NC(=O)[C@H]1CCCc2c1[nH]c1ccc(Cl)cc21
Target:
Sirtuin

References

Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.