C-178

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TargetMol
Product Code: TAR-T7329
Supplier: TargetMol
CodeSizePrice
TAR-T7329-2mg2mg£100.00
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TAR-T7329-5mg5mg£118.00
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TAR-T7329-1mL1 mL * 10 mM (in DMSO)£119.00
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Quantity:
TAR-T7329-10mg10mg£148.00
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Quantity:
TAR-T7329-25mg25mg£229.00
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Quantity:
TAR-T7329-50mg50mg£322.00
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Quantity:
TAR-T7329-100mg100mg£466.00
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TAR-T7329-500mg500mg£946.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
CAS:
329198-87-0
Formula:
C17H10N2O5
Molecular Weight:
322.276
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
[O-][N+](=O)c1ccc(o1)C(=O)Nc1ccc2c(c1)oc1ccccc21
Target:
STING

References

Haag S M , Gulen M F , Luc R , et al. Targeting STING with covalent small-molecule inhibitors[J]. Nature, 2018.