JNJ 303

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TargetMol
Product Code: TAR-T7653
Supplier: TargetMol
CodeSizePrice
TAR-T7653-1mg1mg£103.00
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TAR-T7653-2mg2mg£118.00
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TAR-T7653-5mg5mg£144.00
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TAR-T7653-1mL1 mL * 10 mM (in DMSO)£145.00
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TAR-T7653-10mg10mg£191.00
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TAR-T7653-25mg25mg£346.00
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TAR-T7653-50mg50mg£470.00
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TAR-T7653-100mg100mg£666.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).
CAS:
878489-28-2
Formula:
C21H29ClN2O4S
Molecular Weight:
440.98
Pathway:
Membrane transporter/Ion channel
Purity:
0.9833
SMILES:
CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CC3CC1CC(C3)(C2)NS(C)(=O)=O
Target:
Potassium Channel

References

Kang C , Badiceanu A , Brennan J A , et al. ?-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle[J]. Scientific Reports, 2017, 7(1):15922. Emily R Pfeiffer-Kaushik , Godfrey L Smith , Beibei Cai, et al.Electrophysiological Characterization of Drug Response in hSC-derived Cardiomyocytes Using Voltage-Sensitive Optical Platforms.J Pharmacol Toxicol Methods, 99, 106612 Sep-Oct 2019