UBCS039

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TargetMol
Product Code: TAR-T7679
Supplier: TargetMol
CodeSizePrice
TAR-T7679-1mg1mg£124.00
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TAR-T7679-2mg2mg£148.00
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TAR-T7679-5mg5mg£189.00
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TAR-T7679-1mL1 mL * 10 mM (in DMSO)£207.00
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TAR-T7679-10mg10mg£254.00
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Quantity:
TAR-T7679-25mg25mg£450.00
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TAR-T7679-50mg50mg£624.00
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TAR-T7679-100mg100mg£860.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)
CAS:
358721-70-7
Formula:
C16H13N3
Molecular Weight:
247.301
Pathway:
Autophagy; DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9975
SMILES:
N1C(c2cccn2-c2ccccc12)c1cccnc1
Target:
Sirtuin; Autophagy

References

Miao H, Wang Y, Su W, et al.Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/?-catenin pathway.Acta Pharmacologica Sinica.2023: 1-13. Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.[J]. Cell death & disease, 2018.