TargetMol

HQNO

Product Code:
 
TAR-T8433
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8433-5mg5mg£111.00
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TAR-T8433-10mg10mg£135.00
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TAR-T8433-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T8433-25mg25mg£189.00
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TAR-T8433-50mg50mg£282.00
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TAR-T8433-100mg100mg£436.00
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Further Information

Bioactivity:
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.
CAS:
341-88-8
Formula:
C16H21NO2
Molecular Weight:
259.349
Pathway:
Metabolism
Purity:
0.9923
SMILES:
CCCCCCCc1cc(=O)c2ccccc2n1O
Target:
Mitochondrial Metabolism

References

Kang J , Kim Y J . HQNO-sensitive NADH:Quinone Oxidoreductase of Bacillus cereus KCTC 3674[J]. J Biochem Mol Biol, 2007, 40(1):53-57. Jessica Petri, et al. Structure of the NDH-2 - HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):482-490.