BO-264

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TargetMol
Product Code: TAR-T8492
Supplier: TargetMol
CodeSizePrice
TAR-T8492-1mg1mg£106.00
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TAR-T8492-5mg5mg£148.00
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TAR-T8492-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T8492-10mg10mg£213.00
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TAR-T8492-25mg25mg£294.00
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TAR-T8492-50mg50mg£369.00
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TAR-T8492-100mg100mg£550.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).
CAS:
2408648-20-2
Formula:
C18H19N5O3
Molecular Weight:
353.382
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; Apoptosis
Purity:
0.9981
SMILES:
COc1ccc(cc1)-c1cc(Nc2ccnc(n2)N2CCOCC2)on1
Target:
Apoptosis; FGFR

References

Akbulut O, et al. A Highly Potent TACC3 Inhibitor as a Novel Anti-cancer Drug Candidate. Mol Cancer Ther. 2020 Mar 26. pii: molcanther.0957.2019.