UAMC-3203 hydrochloride

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TargetMol
Product Code: TAR-T8662
Supplier: TargetMol
CodeSizePrice
TAR-T8662-2mg2mg£107.00
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TAR-T8662-5mg5mg£128.00
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TAR-T8662-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T8662-10mg10mg£161.00
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TAR-T8662-25mg25mg£209.00
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TAR-T8662-50mg50mg£242.00
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TAR-T8662-100mg100mg£309.00
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TAR-T8662-200mg200mg£426.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
CAS:
2271358-65-5
Formula:
C25H38ClN5O2S
Molecular Weight:
508.12
Pathway:
Apoptosis; Cell Cycle/Checkpoint
Purity:
0.9987
SMILES:
Cl.O=S(=O)(NCCN1CCNCC1)c1ccc(NC2CCCCC2)c(NCc2ccccc2)c1
Target:
Ferroptosis

References

Yan B, Ai Y, Sun Q, et al. Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1. Molecular Cell. 2020 Yan B, Ai Y, Sun Q, et al. Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1[J]. Molecular Cell. 2020 Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.