iKIX1

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TargetMol
Product Code: TAR-T8722
Supplier: TargetMol
CodeSizePrice
TAR-T8722-1mg1mg£95.00
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TAR-T8722-2mg2mg£106.00
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TAR-T8722-5mg5mg£127.00
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TAR-T8722-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T8722-10mg10mg£177.00
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TAR-T8722-25mg25mg£289.00
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TAR-T8722-50mg50mg£389.00
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TAR-T8722-100mg100mg£547.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection.
CAS:
656222-54-7
Formula:
C10H8Cl2N4OS
Molecular Weight:
303.16
Pathway:
Microbiology/Virology
Purity:
0.9926
SMILES:
Clc1ccc(NC(=S)NNC(=O)CC#N)cc1Cl
Target:
Antifungal

References

Joy L Nishikawa, et al.Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction. Nature. 2016 Feb 25;530(7591):485-9.