LY900009

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TargetMol
Product Code: TAR-T9015
Supplier: TargetMol
CodeSizePrice
TAR-T9015-1mg1mg£114.00
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TAR-T9015-2mg2mg£133.00
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TAR-T9015-5mg5mg£173.00
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TAR-T9015-1mL1 mL * 10 mM (in DMSO)£196.00
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TAR-T9015-10mg10mg£233.00
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TAR-T9015-25mg25mg£362.00
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TAR-T9015-50mg50mg£503.00
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TAR-T9015-100mg100mg£695.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.
CAS:
209984-68-9
Formula:
C23H27N3O4
Molecular Weight:
409.486
Pathway:
Stem Cells; Proteases/Proteasome; Neuroscience
Purity:
0.9897
SMILES:
CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1c2ccccc2-c2ccccc2N(C)C1=O
Target:
Gamma-secretase

References

A first-in-human phase I study of the oral Notch inhibitor, LY900009, in patients with advanced cancer[J]. European Journal of Cancer, 2016, 56.