PFI-90

TargetMol
Product Code: TAR-T9243
Supplier: TargetMol
CodeSizePrice
TAR-T9243-25mg25mg£98.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T9243-1mL1 mL * 10 mM (in DMSO)£114.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action.PFI-90 has the potential for the antitumor activity. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased.
CAS:
53995-62-3
Formula:
C11H10N4O
Molecular Weight:
214.228
Pathway:
Chromatin/Epigenetic;
Purity:
0.995
SMILES:
O=C(NNc1ccccn1)c1ccccn1
Target:
Histone Demethylase;

References

KHAN, Javed, et al. Inhibitors of histone demethylases (pfi-63 and pfi-90) for the treatment of cancer and for the inhibition of histone demethylase in cells. WO2021101929A1.