IXA4

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TargetMol
Product Code: TAR-T9349
Supplier: TargetMol
CodeSizePrice
TAR-T9349-1mg1mg£98.00
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TAR-T9349-5mg5mg£135.00
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TAR-T9349-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T9349-10mg10mg£173.00
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TAR-T9349-25mg25mg£205.00
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TAR-T9349-50mg50mg£288.00
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TAR-T9349-100mg100mg£420.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function.
CAS:
1185329-96-7
Formula:
C24H28N4O4
Molecular Weight:
436.5
Pathway:
Cell Cycle/Checkpoint
Purity:
0.9869
SMILES:
Cc(cc1)ccc1OCCN(C)C(Cn1ncc(NC(CCOc2ccccc2)=O)c1)=O
Target:
IRE1

References

Grandjean JMD, et al. Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nat Chem Biol. 2020;16(10):1052-1061.