Oenothein B
| Code | Size | Price |
|---|
| TAR-TN6732-2mg | 2mg | £310.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.
CAS:
104987-36-2
Formula:
C68H48O44
Molecular Weight:
1569.08
Pathway:
Microbiology/Virology; Proteases/Proteasome; Apoptosis
Purity:
0.98
SMILES:
OC1=C(C(C(O)=C2O)=C(C=C2O)C3=O)C(C(O[C@H]4[C@H](OC(C5=CC(O)=C(O)C(O)=C5)=O)[C@@H](OC(C(C=C6O)=C(C(O)=C6O)OC7=C(O)C(O)=C8C9=C7)=O)[C@H](O)O[C@@H]4CO3)=O)=CC(OC(C(O)=C%10O)=C(C=C%10O)C(O[C@@H]%11[C@@H](OC(C%12=CC(O)=C(O)C(O)=C%12)=O)[C@H](OC(C%13=C8C(O)=C(O)C(O)=C%13)=O)[C@@H](COC9=O)O[C@H]%11O)=O)=C1O
Target:
Apoptosis; HCV Protease; Antibacterial; Antifungal
References
Satoshi Okuyama, et al. Oenothein B suppresses lipopolysaccharide (LPS)-induced inflammation in the mouse brain. Int J Mol Sci. 2013 May 7;14(5):9767-78.
Satoru Tamura, et al. Oenothein B, dimeric hydrolysable tannin inhibiting HCV invasion from Oenothera erythrosepala. J Nat Med. 2019 Jan;73(1):67-75.
Xiaodong Pei, et al. Oenothein B inhibits human non-small cell lung cancer A549 cell proliferation by ROS-mediated PI3K/Akt/NF-?B signaling pathway. Chem Biol Interact. 2019 Jan 25;298:112-120.