TargetMol

Chebulagic acid

Product Code:
 
TAR-TQ0180
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0180-1mg1mg£128.00
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TAR-TQ0180-5mg5mg£205.00
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TAR-TQ0180-10mg10mg£271.00
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TAR-TQ0180-1mL1 mL * 10 mM (in DMSO)£287.00
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TAR-TQ0180-25mg25mg£406.00
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TAR-TQ0180-50mg50mg£571.00
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TAR-TQ0180-100mg100mg£783.00
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Further Information

Bioactivity:
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
CAS:
23094-71-5
Formula:
C41H30O27
Molecular Weight:
954.664
Pathway:
Metabolism; Microbiology/Virology; Immunology/Inflammation; Neuroscience
Purity:
0.998
SMILES:
OC1C2C(CC(O)=O)C(=O)O[C@@H]3[C@H]4COC(=O)c5cc(O)c(O)c(O)c5-c5c(O)c(O)c(O)cc5C(=O)O[C@@H]3[C@@H](OC(=O)c3cc(O)c(O)c(OC1=O)c23)[C@@H](OC(=O)c1cc(O)c(O)c(O)c1)O4
Target:
SARS-CoV; Influenza Virus; Lipoxygenase; COX

References

Liu Y et al. Chebulagic acid inhibits the LPS-induced expression of TNF-? and IL-1? in endothelial cells by suppressing MAPK activation. Exp Ther Med. 2015 Jul;10(1):263-268. Kim HJ et al. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomol Ther (Seoul). 2014 Jul;22(4):275-81. Athira AP et al. Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor. Int J Vasc Med. 2013;2013:843897.