Chebulinic acid
Code | Size | Price |
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TAR-TQ0184-1mg | 1mg | £124.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0184-5mg | 5mg | £197.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0184-10mg | 10mg | £255.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0184-1mL | 1 mL * 10 mM (in DMSO) | £295.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0184-25mg | 25mg | £464.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0184-50mg | 50mg | £655.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0184-100mg | 100mg | £863.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0184-500mg | 500mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
CAS:
18942-26-2
Formula:
C41H32O27
Molecular Weight:
956.68
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Stem Cells; Membrane transporter/Ion channel; Microbiology/Virology
Purity:
0.9891
SMILES:
[H][C@@]12OC(=O)[C@@H](CC(O)=O)[C@]3([H])[C@@H](O)C(=O)Oc4c(O)c(O)cc(c34)C(=O)O[C@@]([H])([C@H](OC(=O)c3cc(O)c(O)c(O)c3)O[C@@H]1COC(=O)c1cc(O)c(O)c(O)c1)[C@@]2([H])OC(=O)c1cc(O)c(O)c(O)c1
Target:
ATPase; Proton pump; DNA/RNA Synthesis; Antibacterial; TGF-beta/Smad
References
Mishra V et al. Anti-secretory and cyto-protective effects of chebulinic acid isolated from the fruits of Terminalia chebula on gastric ulcers. Phytomedicine. 2013 Apr 15;20(6):506-11.
Zong-Chun Yi, et al. Chebulinic Acid and Tellimagrandin I Inhibit DNA Strand Breaks by hydroquinone/Cu(II) and H(2)O(2)/Cu(II), but Potentiate DNA Strand Breaks by H(2)O(2)/Fe(II). Toxicol In Vitro. Jun 2009; 23 (4), 667-73
Y Y Guan, et al. In Vitro Inhibitory Effects of Chebulinic Acid on the Contractile Responses of Cardiovascular Muscles. Clin Exp Pharmacol Physiol. Aug 1996 23 (8), 747-50