Metyrapone Tartrate
| Code | Size | Price |
|---|
| TAR-T0293L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Metyrapone Tartrate is an inhibitor of the STEROID 11-beta-monooxygenase enzyme which is used as a test for feedback hypothalamic-pituitary mechanism in the diagnosis of Cushing SYNDROME.
CAS:
908-35-0
Formula:
C22H26N2O13
Molecular Weight:
526.451
Purity:
0.98
SMILES:
O[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC(C)(C(=O)c1cccnc1)c1cccnc1
References
1. Weiler U, Finsler S, Claus R. Influence of cortisol, gonadal steroids and an energy deficit on biochemical indicators of bone turnover in Swine. J Vet Med A Physiol Pathol Clin Med. 2003 Mar;50(2):79-87. PubMed PMID: 12667198.
2. Dickstein G, Spindel A, Shechner C, Adawi F, Gutman H. Spontaneous remission in Cushing's disease. Arch Intern Med. 1991 Jan;151(1):185-9. Review. PubMed PMID: 1985595.
3. Mito T, Shiono T, Kimura R, Tamai M. The effect of oral metyrapone on aqueous humor dynamics in normal human eyes. Acta Ophthalmol (Copenh). 1990 Oct;68(5):582-6. PubMed PMID: 2275356.
4. Galinsky RE, Corcoran GB. Suppression of acetaminophen conjugation and of conjugate elimination in the rat by metyrapone, a classical P-450 inhibitor. Drug Metab Dispos. 1988 May-Jun;16(3):348-54. PubMed PMID: 2900724.