Pyrantel
| Code | Size | Price |
|---|
| TAR-T0395L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Pyrantel is a nicotinic receptor agonist and a depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes.
CAS:
15686-83-6
Formula:
C11H14N2S
Molecular Weight:
206.31
Purity:
0.98
SMILES:
CN1CCCN=C1C=Cc1cccs1
References
1. Abongwa M, Buxton SK, Robertson AP, Martin RJ. Curiouser and Curiouser: The Macrocyclic Lactone, Abamectin, Is also a Potent Inhibitor of Pyrantel/Tribendimidine Nicotinic Acetylcholine Receptors of Gastro-Intestinal Worms. PLoS One. 2016 Jan 11;11(1):e0146854. doi: 10.1371/journal.pone.0146854. eCollection 2016. PubMed PMID: 26751958; PubMed Central PMCID: PMC4709073.
2. Klausz G, Keller ?, S?ra Z, Sz?kely-K?rm?czy P, Laczay P, Ary K, S?tonyi P, R?na K. Simultaneous determination of praziquantel, pyrantel embonate, febantel and its active metabolites, oxfendazole and fenbendazole, in dog plasma by liquid chromatography/mass spectrometry. Biomed Chromatogr. 2015 Dec;29(12):1859-65. doi: 10.1002/bmc.3507. Epub 2015 Jun 24. PubMed PMID: 26104502.
3. Lawson E, Burden F, Elsheikha HM. Pyrantel resistance in two herds of donkey in the UK. Vet Parasitol. 2015 Jan 30;207(3-4):346-9. doi: 10.1016/j.vetpar.2014.12.026. Epub 2014 Dec 30. PubMed PMID: 25576440.
4. Armstrong SK, Woodgate RG, Gough S, Heller J, Sangster NC, Hughes KJ. The efficacy of ivermectin, pyrantel and fenbendazole against Parascaris equorum infection in foals on farms in Australia. Vet Parasitol. 2014 Oct 15;205(3-4):575-80. doi: 10.1016/j.vetpar.2014.08.028. Epub 2014 Sep 6. PubMed PMID: 25224788.