TargetMol

VEGFR-2-IN-9

Product Code:
 
TAR-T10123
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10123-5mg5mg£930.00
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Quantity:
TAR-T10123-50mg50mg£1,821.00
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Quantity:
TAR-T10123-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
KDR-in-4 is an effective inhibitor of kinase insert domain-containing receptor (KDR/VEGFR2) (IC50: 7 nM).
CAS:
408502-06-7
Formula:
C23H25N3O3
Molecular Weight:
391.471
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.98
SMILES:
COCCN(C)CCOc1ccc2[nH]c(cc2c1)-c1cc2ccccc2[nH]c1=O
Target:
VEGFR

References

1. Fang YQ, et al. Efficient syntheses of KDR kinase inhibitors using a Pd-catalyzed tandem C-N/Suzuki coupling as the key step. J Org Chem. 2007 Feb 16;72(4):1341-6. 2. Kinose F, et al. Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor. Molecular Vision 2005; 11:366-373