TargetMol

ACHN-975

Product Code:
 
TAR-T10236L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10236L-5mg5mg£1,572.00
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TAR-T10236L-50mg50mg£3,107.00
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Quantity:
TAR-T10236L-100mg100mg£4,247.00
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This product comes from: United States.
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Further Information

Bioactivity:
ACHN-975 is against a wide range of gram-negative bacterias with low MIC values (?1 μg/mL)[1]. ACHN-975 is a selective LpxC inhibitor and exhibits a subnanomolar LpxC inhibitory activity.
CAS:
1410809-36-7
Formula:
C20H23N3O4
Molecular Weight:
369.421
Purity:
0.98
SMILES:
CC(C)(N)[C@H](NC(=O)c1ccc(cc1)C#CC#C[C@@H]1C[C@H]1CO)C(=O)NO

References

1. Kalinin DV, et al. Insights into the Zinc-Dependent Deacetylase LpxC: Biochemical Properties and Inhibitor Design. Curr Top Med Chem. 2016;16(21):2379-430. 2. Krause KM,et al. Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa.Antimicrob Agents Chemother. 2019 Oct 22;63(11). pii: e00977-19.