AOH1160

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TargetMol
Product Code: TAR-T10343
Supplier: TargetMol
CodeSizePrice
TAR-T10343-5mg5mg£111.00
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TAR-T10343-1mL1 mL * 10 mM (in DMSO)£128.00
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Quantity:
TAR-T10343-10mg10mg£131.00
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Quantity:
TAR-T10343-25mg25mg£173.00
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Quantity:
TAR-T10343-50mg50mg£225.00
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Quantity:
TAR-T10343-100mg100mg£301.00
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TAR-T10343-200mg200mg£417.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.
CAS:
2089314-57-6
Formula:
C25H20N2O3
Molecular Weight:
396.446
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Apoptosis
Purity:
0.9916
SMILES:
O=C(CNC(=O)c1cccc2ccccc12)Nc1ccccc1Oc1ccccc1
Target:
Apoptosis; DNA/RNA Synthesis

References

1. Gu L, et al. The Anticancer Activity of a First-in-class Small-molecule Targeting PCNA. Clin Cancer Res. 2018 Dec 1;24(23):6053-6065.