Lisaftoclax

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TargetMol
Product Code: TAR-T10483
Supplier: TargetMol
CodeSizePrice
TAR-T10483-1mg1mg£322.00
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TAR-T10483-5mg5mg£625.00
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TAR-T10483-1mL1 mL * 10 mM (in DMSO)£858.00
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TAR-T10483-10mg10mg£867.00
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TAR-T10483-25mg25mg£1,251.00
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TAR-T10483-50mg50mg£1,661.00
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TAR-T10483-100mg100mg£2,223.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Lisaftoclax is a dual Bcl-2 and Bcl-xl inhibitor (IC50: 2 nM and 5.9 nM) with antitumor activity.
CAS:
2180923-05-9
Formula:
C45H48ClN7O8S
Molecular Weight:
882.42
Pathway:
Apoptosis
Purity:
0.9714
SMILES:
C(C1=C(CC2(CC1)CCC2)C3=CC=C(Cl)C=C3)N4CCN(CC4)C5=CC(OC=6C=C7C(=NC6)NC=C7)=C(C(NS(=O)(=O)C8=CC(N(=O)=O)=C(NC[C@H]9COCCO9)C=C8)=O)C=C5
Target:
BCL

References

1. WANG, Chia, et al. N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS. Patent. WO2018027097A1.