YM158 free base
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).
CAS:
179102-65-9
Formula:
C32H33ClN6O5S2
Molecular Weight:
681.22
Purity:
0.98
SMILES:
CC(C)(C)c1csc(COc2cccc(c2)C(=O)Nc2cc(CCCS(=O)(=O)c3ccc(Cl)cc3)ccc2OCc2nnn[nH]2)n1
References
1. Arakida Y, et al. In vitro pharmacologic profile of YM158, a new dual antagonist for LTD
2. Arakida Y, et al. Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. J Pharmacol Exp Ther. 1999 Sep;290(3):1285-91.