TargetMol

Biotin-VAD-FMK

Product Code:
 
TAR-T10548
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10548-5mg5mg£457.00
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This product comes from: United States.
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Further Information

Bioactivity:
Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active caspases in cell lysates.
CAS:
1135688-15-1
Formula:
C30H49FN6O8S
Molecular Weight:
672.81
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(C)C)C(=O)CF
Target:
Caspase

References

1. Li J, et al. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. J Biol Chem. 1999 Jun 11;274(24):17325-33. 2. Samraj AK, et al. Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membranedepolarization. Mol Biol Cell. 2007 Jan;18(1):84-93.