TargetMol

CCT365623 hydrochloride

Product Code:
 
TAR-T10719
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10719-5mg5mg£630.00
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TAR-T10719-50mg50mg£1,982.00
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Quantity:
TAR-T10719-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.
CAS:
2126136-98-7
Formula:
C18H18ClNO4S3
Molecular Weight:
443.98
Pathway:
Metabolism
Purity:
0.98
SMILES:
Cl.CS(=O)(=O)c1cc(cc(c1)S(=O)(=O)c1ccc(CN)s1)-c1ccccc1
Target:
Lipoxygenase

References

1. Tang H, et al. Author Correction: Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface. Nat Commun. 2019 Jul 18;10(1):3151.